References

Mulder, G, Tallis A, Marshall T, Mozingo, D, Phillips, L, Pierce, G, Chandler L, Sosnowski B. Treatment of Nonhealing Diabetic Foot Ulcers with a Platelet-Derived Growth Factor Gene-Activated Matrix (GAM501): Results of a Phase 1/2 trial. Wound Repair and Regeneration. 17(6): 772-779 (2009).

Chang PC, Seol YJ, Cirelli JA, Pellegrini G, Jin Q, Franco LM, Goldstein SA, Chandler LA, Sosnowski B, Giannobile WV. PDGF-B gene therapy accelerates bone engineering and oral implant osseointegration. Gene Therapy (10 September 2009) doi:10.1038/gt.2009.117

Chang PC, Cirelli JA, Jin Q, Seol YJ, Sugai JV, D'Silva NJ, Danciu TE, Chandler LA, Sosnowski BA, Giannobile WV. Adenovirus Encoding Human Platelet-Derived Growth Factor-B Delivered to Alveolar Bone Defects Exhibits Safety and Biodistribution Profiles Favorable for Clinical Use. Hum Gene Ther. 20:486-496 (2009).

Schreiber RE, Blease K, Ambrosio A, Amburn E, Sosnowski B, Sampath TK. Bone induction by AdBMP-2/collagen implants. J Bone Joint Surg Am. 87(5):1059-68 (2005).

Gu DL, Nguyen T, Phillips L., Chandler LA, Sosnowski B. Matrix-immobilized growth factor gene therapy enhances tissue repair. Wounds 16(1): 34-41 (2004).

Gu DL, Nguyen T, Gonzalez AM, Printz MA, Pierce GF, Sosnowski BA, Phillips ML, Chandler LA. Adenovirus encoding human platelet-derived growth factor-B delivered in collagen exhibits safety, biodistribution, and immunogenicity profiles favorable for clinical use. Mol Ther. 9(5):699-711 (2004).

Doukas J, Chandler LA, Gonzalez AM, Gu D, Hoganson DK, Ma C, Nguyen T, Printz MA, Nesbit M, Herlyn M, Crombleholme TM, Aukerman SL, Sosnowski BA, Pierce GF. Matrix immobilization enhances the tissue repair activity of growth factor gene therapy vectors. Hum Gene Ther. 12(7):783-98 (2001).

Chandler LA, Gu DL, Ma C, Gonzalez AM, Doukas J, Nguyen T, Pierce GF, Phillips ML. Matrix-enabled gene transfer for cutaneous wound repair. Wound Repair Regen. 8(6):473-9 (2000).